The majority of performance horses have ulcers, either gastric or colonic. Equine ulcers can be painful and lead to a number of symptoms for horses young and old.

In adult horses, gastric ulcers occur more frequently in horses that perform athletic activities, with the highest frequency found in thoroughbred racehorses (80-90%), followed by endurance horses (70%), then show horses (60%). Researchers have found that exercise increases gastric acid production and decreases blood flow to the gastrointestinal (GI) tract.

There are many different reasons equine ulcers occur but horses with stomach ulcers do not often exhibit any obvious clinical signs and horse owners often do not know that their horses are actually suffering in silence. 

Only your local veterinarian can accurately diagnose equine stomach ulcers, but you as a horseman can help by looking for changes in your horse and reporting them to your veterinarian.

What are the signs of equine ulcers?

Here are a few signs to look for:

  • Change in eating and drinking behavior
  • Change in attitude (for the worse)
  • Weight loss
  • Dull and dry hair coat
  • Poor performance
  • Recurrent colic
  • Foals may also possibly grind their teeth and/or lay on their backs
  • Poor eaters, then think ULCERS.

Tips for Trainers:  Respond quickly to treat painful equine stomach ulcers.  The faster you respond to equine stomach (gastric) ulcers, the greater your chance of reducing the painful and damaging effects of this serious condition.  That’s why an accurate and timely diagnosis is critical and why it is important to begin a treatment program as soon as symptoms begin.

How can I treat equine ulcers?

Omeprazole Paste

Omeprazole Paste is used to treat painful stomach ulcers in horses and works to suppress the stomach acids that cause ulcers in horses. Omeprazole Paste also prevents equine gastric ulcer syndrome, which can be a painful condition for horses. The oral paste is delivered via a syringe that is administered to horses every day as needed.

MORE: How To Treat Ulcers In Horses Without Using Omeprazole Paste

Omeprazole aids horses natural functions in the reducing gastric acid and the general acidity of the stomach. Because a horse’s stomach is relatively small and cannot handle large amounts of feed, it must eat frequent, small portions of feed.

Since horses are grazers and in most cases are confined to a stall, roughage intake is interrupted and acidity increases, which can lead to ulceration or eating away at the stomach’s protective lining.

Omeprazole Paste stops stomach acid production at its source by inhibiting the acid pump.  This allows Omeprazole Paste to provide superior treatment and healing of equine stomach ulcers because its mode of action blocks acid secretion, regardless of the stimulus.

Misoprostol Powder

Like Omeprazole Paste, Misoprostol Powder (1.4 mg/scoop – 30 scoops) is a prescription medication for the treatment and prevention of stomach ulcers, especially those due to the use of non-steroidal anti-inflammatory drugs such as aspirin and other NSAIDS.

Misoprostol treats and prevents colonic equine ulcers by protecting the stomach lining and also decreasing stomach acid formation.

Misoprostol is one of the only drugs to actually treat painful colonic (hind end) ulcers.  Sixty-five percent of all horses have painful colonic ulcers.  Misoprostol is a synthetic form of a prostaglandin.

Cimetidine Powder

Similarly, Cimetidine Powder may be used to aid in the treatment of existing equine ulcers and help prevent the development of equine ulcers. Cimetidine Powder may also be used in the treatment of reflux or to reduce inflammation of the esophagus or stomach.

Cimetidine is a histamine H2-receptor antagonist that inhibits stomach acid production.  It is largely used in humans and animals for the treatment of painful heartburn and peptic ulcers.

Cimetidine belongs to the class of medications called histamine H2-antagonists.  Histamine is a natural chemical in the body that stimulates stomach cells to produce stomach acid.  Histamine H2-antagonists inhibits the action of histamine on the acid producing cells of the stomach thereby reducing stomach acid.  


Lastly, Ranitidine is a histamine H2-receptor antagonist that inhibits stomach acid production.  It is largely used in humans and animals for the treatment of peptic ulcers  and heartburn.

Ranitidine belongs to the class of medications called histamine H2-antagonists as does Cimetidine. 

Where can I buy medicine for equine ulcers?

Racing supplements are part of horse racing. is an international supplier of veterinary products to maintain the health of your racing animal and to maximize their performance.

Click here to see the line of ulcer supplements from

Racehorse Meds accepts all major credit cards and even accepts BitCoin as a form of payment. In addition to Misoprostol Powder and Omeprazole Paste, Racehorse Meds’ user-friendly online store offers a number of supplement and vitamin choices ranging from Amino Acid, Vitamin & Mineral Supplements and Calming Products and Sedatives, to Joint Supplements and even Performance Supplements.

MORE: Picking The Best Joint Supplements For Your Horse

For more information about horse racing and other animal racing supplements, visit Racehorse Meds. Racehorse Meds is you trusted veterinary supplier of vitamins and supplements for horses, camels, alpacas, greyhounds, and pigeons.

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